NCIt definition : An assay that measures the proliferative response of lymphocytes from one individual
when they are exposed to inactivated lymphocytes from another individual. The reaction
can be performed on lymphocytes from the same individual (auto-MLR), from different
individuals of the same species (allo-MLR), or individuals from different species
(xeno-MLR). It is used to evaluate the potential for graft-versus-host or host-versus-graft
reactions during transplantation procedures involving mismatched tissue types or individuals.;
Alternative definition : CDISC: A measurement of the histocompatibility at the HL-A locus between two populations
of lymphocytes taken from two separate individuals.;