" /> lymphocyte culture test, mixed - CISMeF





Preferred Label : lymphocyte culture test, mixed;

MeSH definition : Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.;

MeSH synonym : leukocyte reactions, mixed; lymphocyte reactions, mixed; mixed leukocyte reaction; mixed lymphocyte culture test; mixed lymphocyte reaction; leukocyte culture test, mixed; lymphocyte reaction, mixed; leukocyte reaction, mixed; mixed leukocyte reactions; mixed leukocyte culture test; mixed lymphocyte reactions;

MeSH annotation : NIM;

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Keyword's position in hierarchy(ies) : arborescence

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Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.

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09/05/2025


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