Fluorine F 18 NOS

Preferred Label : Fluorine F 18 NOS;

NCIt synonyms : FNOS; 18F NOS; (18)F-NOS; [18F]NOS; 18F-NOS;

NCIt related terms : NOS F-18;

NCIt definition : A radiotracer composed of an analog of the reversible nitric oxide synthase (NOS) inhibitor, 2-amino 4-methylpyridine, radiolabeled with fluorine F 18, with potential imaging activity upon positron emission tomography/computed tomography (PET/CT). Upon administration of fluorine F 18 NOS, the NOS moiety targets and binds to inducible NOS (iNOS). Upon PET/CT imaging, iNOS expression and thus the extent of inflammation can be assessed. iNOS expression is upregulated in a variety of inflammatory diseases and certain cancers and may invoke a chronic inflammatory state in tumor cells.;

UNII : YTN3P8TA3K;

CAS number : 1146620-79-2;

NCI Metathesaurus CUI : CL972444;

Details

Origin ID

C167219;

UMLS CUI

C0302995;

Semantic type(s)
- Element, Ion, or Isotope [UMLS semantic type]
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
UMLS correspondences (same concept)
- 18 fluorine [SNOMED Notion]
- Fluorine-18 [MeSH Supplementary Concept]
- Fluorine-18 (substance) [SNOMED CT concept]
- Product containing fluorine-18 (medicinal product) [SNOMED CT concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Nitric Oxide Synthase, Inducible [NCIt concept]

Keyword's position in hierarchy(ies) :

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