" /> Firastotug - CISMeF





Preferred Label : Firastotug;

NCIt synonyms : Anti-CTLA-4 Monoclonal Antibody ADG116;

NCIt definition : A human monoclonal antibody directed against the human T-cell-expressed receptor cytotoxic T-lymphocyte-associated antigen 4 (CTLA4; CTLA-4), with potential immune checkpoint inhibitory and antineoplastic activities. Upon intravenous administration, firastotug targets and binds to CTLA-4 expressed on T-cells and inhibits the CTLA-4-mediated downregulation of T-cell activation. This leads to a cytotoxic T-lymphocyte (CTL)-mediated immune response against cancer cells, thereby killing cancer cells. CTLA-4, an inhibitory receptor and member of the immunoglobulin superfamily (IgSF), plays a key role in the downregulation of the immune system.;

UNII : 8B1J60R28A;

CAS number : 2750031-14-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2750031-14-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : ADG 116; ADG-116;

NCI Metathesaurus CUI : CL979207;

Details


You can consult :


Nous contacter.
15/05/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.