Preferred Label : Gene Amplification;
NCIt synonyms : Transcript Amplification;
NCIt related terms : Amplification;
NCIt definition : Any DNA sequence rearrangement that results in the gain of one or more copies of a
DNA segment that contains at least one gene.;
Alternative definition : NCI-GLOSS: An increase in the number of copies of a gene. There may also be an increase
in the RNA and protein made from that gene. Gene amplification is common in cancer
cells, and some amplified genes may cause cancer cells to grow or become resistant
to anticancer drugs. Genes may also be amplified in the laboratory for research purposes.;
Codes from synonyms : CDR0000650175;
Origin ID : C16605;
UMLS CUI : C0017256;
Semantic type(s)
- UMLS correspondences (same concept)
