" /> Warfarin Sodium - CISMeF





Preferred Label : Warfarin Sodium;

NCIt synonyms : Tintorane; Prothromadin;

NCIt related terms : Coumadin; Panwarfin;

NCIt definition : The sodium salt form of warfarin, a coumarin and a vitamin K antagonist, with anticoagulant activity. Warfarin sodium inhibits both vitamin K and vitamin K epoxide reductases, thereby interfering with the cyclic interconversion of vitamin K epoxide to its reduced form, vitamin KH2. Vitamin KH2 is a cofactor for the carboxylation of glutamate residues on the N-terminal regions of vitamin K-dependent proteins. As a result, maturation of vitamin K-dependent coagulation factors II, VII, IX, and X and anticoagulant proteins C and S is inhibited. Without these coagulation factors, thrombogenesis and blood clot formation are prevented.;

UNII : 6153CWM0CL;

InChIKey : KYITYFHKDODNCQ-UHFFFAOYSA-M;

CAS number : 129-06-6;

Drug name : Marevan; Coumadin; Warfilone; Waran; Panwarfin;

Chemical formula : C19H15O4.Na;

ChEBI ID : CHEBI:10034;

Codes from synonyms : NSC0059813;

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09/05/2025


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