" /> Tuspetinib - CISMeF





Preferred Label : Tuspetinib;

NCIt synonyms : FMS-like Tyrosine Kinase 3 Inhibitor HM43239; FLT3 Inhibitor HM43239;

NCIt definition : A selective, reversible type I inhibitor of FMS-like tyrosine kinase 3 (FLT3; CD135; STK1; FLK2) with potential antineoplastic activity. Upon administration, tuspetinib reversibly binds to and inhibits the activity of FLT3. This inhibits the proliferation of FLT3-expressing cancer cells. FLT3, a class III receptor tyrosine kinase (RTK), is overexpressed or mutated in most B-lineage neoplasms and in acute myeloid leukemias.;

UNII : C0WUS7XXE9;

CAS number : 2294874-49-8;

Molecule name : HM-43239; HM 43239;

NCI Metathesaurus CUI : CL978555;

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10/07/2025


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