Preferred Label : Tuspetinib;
NCIt synonyms : FMS-like Tyrosine Kinase 3 Inhibitor HM43239; FLT3 Inhibitor HM43239;
NCIt definition : A selective, reversible type I inhibitor of FMS-like tyrosine kinase 3 (FLT3; CD135;
STK1; FLK2) with potential antineoplastic activity. Upon administration, tuspetinib
reversibly binds to and inhibits the activity of FLT3. This inhibits the proliferation
of FLT3-expressing cancer cells. FLT3, a class III receptor tyrosine kinase (RTK),
is overexpressed or mutated in most B-lineage neoplasms and in acute myeloid leukemias.;
UNII : C0WUS7XXE9;
CAS number : 2294874-49-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2294874-49-8
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Molecule name : HM-43239; HM 43239;
NCI Metathesaurus CUI : CL978555;
Origin ID : C165254;
UMLS CUI : C5706656;
Semantic type(s)
- concept_is_in_subset
- has_target
