DNA Damage - CISMeF

Preferred Label : DNA Damage;

NCIt definition : Drug-, radiation-induced, or spontaneous injuries to DNA that introduce deviations from its normal double-helical conformation. These changes include structural distortions that interfere with replication and transcription, as well as point mutations that disrupt base pairs and exert damaging effects on future generations through changes in DNA sequence. If the damage is minor, it can often be repaired (DNA repair); extensive damage can induce apoptosis.;

Details

Origin ID

C16507;

UMLS CUI

C0012860;

Currated CISMeF NLP mapping
- DNA damage [Disease (Nov.)]
- DNA damage [MeSH concept]
- Deoxyribonucleic acid damage (finding) [SNOMED CT concept]
- dna damage [MeSH Descriptor]
- dna damage [SNOMED Notion]
Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
UMLS correspondences (same concept)
- DNA damage [Disease (Nov.)]
- DNA damage [MeSH concept]
- Deoxyribonucleic acid damage (finding) [SNOMED CT concept]
- dna damage [SNOMED Notion]
- dna damage [MeSH Descriptor]
biological_process_has_associated_location
- Chromosome Structure [NCIt concept]
biological_process_has_result_biological_process
- DNA Repair [NCIt concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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