Preferred Label : Foslinanib Disodium;
NCIt synonyms : TRX818 Disodium; CVM-1118 Disodium; 4(1H)-Quinolinone, 2-(3-Fluorophenyl)-6-methoxy-5-(phosphonooxy)-, Sodium Salt (1:2);
NCIt definition : The disodium salt form of foslinanib, an orally bioavailable agent with potential
antineoplastic and anti-vasculogenic mimicry activities. Upon oral administration,
foslinanib targets and inhibits the formation of vasculogenic mimicry (VM; vascular
mimicry). By destroying the VM channels and network, cancer cells are devoid of perfusion
leading to an induction of cancer cell apoptosis and inhibition of cancer cell proliferation.
VM is associated with tumor metastasis.;
UNII : 8X5F5LAF7B;
InChIKey : TWMCXXQLLQDSTN-UHFFFAOYSA-L;
CAS number : 1256037-62-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1256037-62-3
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Molecule name : TRX-818;
NCI Metathesaurus CUI : CL977259;
Origin ID : C163994;
UMLS CUI : C5235880;
Semantic type(s)
- concept_is_in_subset
