" /> Foslinanib - CISMeF





Preferred Label : Foslinanib;

NCIt synonyms : 4(1H)-Quinolinone, 2-(3-Fluorophenyl)-6-methoxy-5-(phosphonooxy)-; WHO 10721;

NCIt definition : An orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry activities. Upon oral administration, foslinanib targets and inhibits the formation of vasculogenic mimicry (VM; vascular mimicry). By destroying the VM channels and network, cancer cells are devoid of perfusion leading to an induction of cancer cell apoptosis and inhibition of cancer cell proliferation. VM is associated with tumor metastasis.;

UNII : 2X2DNM7NGX;

InChIKey : ZDWFMAHQGDEALT-UHFFFAOYSA-N;

CAS number : 1256037-60-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1256037-60-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : TRX-818; CVM-1118; CVM 1118; TRX 818;

NCI Metathesaurus CUI : CL498218;

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12/05/2024


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