Preferred Label : Foslinanib;
NCIt synonyms : 4(1H)-Quinolinone, 2-(3-Fluorophenyl)-6-methoxy-5-(phosphonooxy)-; WHO 10721;
NCIt definition : An orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry
activities. Upon oral administration, foslinanib targets and inhibits the formation
of vasculogenic mimicry (VM; vascular mimicry). By destroying the VM channels and
network, cancer cells are devoid of perfusion leading to an induction of cancer cell
apoptosis and inhibition of cancer cell proliferation. VM is associated with tumor
metastasis.;
UNII : 2X2DNM7NGX;
InChIKey : ZDWFMAHQGDEALT-UHFFFAOYSA-N;
CAS number : 1256037-60-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1256037-60-1
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G-SRS /a ;
Molecule name : TRX-818; CVM-1118; CVM 1118; TRX 818;
NCI Metathesaurus CUI : CL498218;
Origin ID : C123824;
UMLS CUI : C5235381;
- Semantic type(s)
- concept_is_in_subset