Alpha-Conotoxin GI

Preferred Label : Alpha-Conotoxin GI;

NCIt synonyms : Alpha-GI;

NCIt definition : A 13-amino acid alpha-conotoxin that is isolated from the venom of the cone snail Conus geographus. It is a competitive antagonist of the muscle-type nicotinic acetylcholine receptors, blocking synaptic transmission at the neuromuscular junction. Alpha-conotoxins are identified by a characteristic arrangement of four-cysteine residues (-CC-C-C-) and disulfide bonding of Cys1-Cys3 and Cys2-Cys4.;

Alternative definition : CDISC: The biotoxin alpha-conotoxin GI.;

CAS number : 76862-65-2;

NCI Metathesaurus CUI : CL976906;

Details

Origin ID

C163582;

UMLS CUI

C0244111;

Automatic exact mappings (from CISMeF team)
- alpha-conotoxin GI [MeSH concept]
- conotoxin GI [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
- Hazardous or Poisonous Substance [UMLS semantic type]
UMLS correspondences (same concept)
- alpha-conotoxin GI [MeSH concept]
concept_is_in_subset
- CDISC SEND Chemical Challenge Agent Name Response Terminology [NCIt concept]
- CDISC SEND Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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