Preferred Label : Alpha-Conotoxin Ac1.1A;
NCIt synonyms : Alpha-Ac1.1a;
NCIt definition : A 17-amino acid alpha3/5-conotoxin isolated from the venom of the cone snail Conus
achatinus that is a competitive antagonist of the muscle-type nicotinic acetylcholine
receptors, blocking synaptic transmission at the neuromuscular junction. Alpha-conotoxins
are identified by a characteristic arrangement of four-cysteine residues (-CC-C-C-)
and disulfide bonding of Cys1-Cys3 and Cys2-Cys4. In addition, alpha3/5-conotoxins
are further classified as having three residues in the first intercysteine loop and
five residues in the second intercysteine loop.;
Alternative definition : CDISC: The biotoxin alpha-conotoxin Ac1.1a.;
NCI Metathesaurus CUI : CL976939;
Origin ID : C163579;
UMLS CUI : C5235580;
Semantic type(s)
- concept_is_in_subset
