Actin - CISMeF

Preferred Label : Actin;

NCIt definition : A globular subunit of microfilaments, highly conserved Actin is one of the most abundant proteins in eukaryotic cells. Monomeric actin, a slow ATPase composed of a 375 amino acid polypeptide chain, interacts with one molecule of ATP or ADP and contains high affinity and low affinity binding sites for divalent cations. Actin can quickly assemble into long microfilament polymers. In conjunction with myosin, actin is responsible for the contraction and relaxation of muscle.;

Details

Origin ID

C16258;

UMLS CUI

C0001271;

Automatic exact mappings (from CISMeF team)
- Actinic (qualifier value) [SNOMED CT concept]
- Fibrillar actin [FMA entity]
- Globular actin [FMA entity]
- actinic [IUPAC Term]
- actinism [IUPAC Term]
- sea anemone [SNOMED Notion]
Currated CISMeF NLP mapping
- Actin [LOINC component]
- Actin [FMA entity]
- actin [SNOMED Notion]
- actins [MeSH Descriptor]
- actins [MeSH concept]
False automatic mappings
- Actin (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Actin [LOINC component]
- Actin [FMA entity]
- Actin (substance) [SNOMED CT concept]
- actin [SNOMED Notion]
- actins [MeSH Descriptor]
- actins [MeSH concept]
gene_encodes_gene_product
- Cytoskeletal Gene [NCIt concept]
- Microfilament Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Actin Filament [NCIt concept]
- Cytoskeleton [NCIt concept]
gene_product_has_biochemical_function
- Scaffolding Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- ATP Hydrolysis [NCIt concept]
- Cell Motility [NCIt concept]
- Cell Movement [NCIt concept]
- Cell Movement Process [NCIt concept]
- Cytoskeletal Process [NCIt concept]
- Regulation of Cell Shape [NCIt concept]

Keyword's position in hierarchy(ies) :

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