Glufosfamide - CISMeF

Preferred Label : Glufosfamide;

NCIt synonyms : Beta-D-Glucosyl-Ifosfamide Mustard; glc-IPM;

NCIt definition : A compound consisting of the mustard agent ifosforamide conjugated to glucose, with potential alkylating activity. Glufosfamide is cleaved by glucosidases in tumor cells and forms ifosforamide. In turn, ifosforamide alkylates and forms DNA crosslinks, thereby inhibiting DNA replication and subsequent cell growth. The glucose moiety may enhance this agent's uptake by tumor cells.;

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called alkylating agents.;

UNII : 1W5N8SZD9A;

InChIKey : PSVUJBVBCOISSP-SPFKKGSWSA-N;

CAS number : 132682-98-5;

Molecule name : D-19575;

Chemical formula : C10H21Cl2N2O7P;

Codes from synonyms : CDR0000045540;

Details

Origin ID

C1612;

UMLS CUI

C0912322;

Currated CISMeF NLP mapping
- glucosyl-ifosfamide mustard [MeSH concept]
See also inter- (CISMeF)
- beta-D-glucosylisophosphoramide mustard [MeSH Supplementary Concept]
- beta-D-glucosylisophosphoramide mustard [MeSH concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- glucosyl-ifosfamide mustard [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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