" /> Labradimil - CISMeF





Preferred Label : Labradimil;

NCIt synonyms : L-Prolinamide, L-Arginyl-L-prolyl-trans-4- hydroxy-L-prolyl-3-(2- thienyl)-L-alanylglycl -L-seryl-N-(2-((4-((aminoiminomethyl)amino)-1- -carboxybutyl)amino)-1-((4-methoxyphenyl)methyl)ethyl)-, (S-(R*,R*)); Lobradimil;

NCIt related terms : RMP-7;

NCIt definition : A synthetic analog of bradykinin. Lobradimil is a potent, specific bradykinin B-2 receptor agonist that stimulates B-2 receptors expressed on the surface of brain capillary endothelial cells, thereby reversibly increasing the permeability of the blood-brain barrier (BBB). Compared to bradykinin, this agent possesses enhanced receptor selectivity, greater plasma stability, and a longer half-life. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is being studied for its ability to help other drugs reach the brain. It belongs to the family of drugs called bradykinin agonists.;

UNII : 2MK663C346;

InChIKey : IDXCXSCCZNCXCL-XMADEQCMSA-N;

CAS number : 159768-75-9;

Drug name : Cereport;

Molecule name : DRG-0182;

Chemical formula : C49H75N15O12S;

NSC code : 950021;

Codes from synonyms : CDR0000367477; CDR0000045461;

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02/05/2025


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