Prostate Adenocarcinoma with Paneth Cell-Like Neuroendocrine Differentiation

Preferred Label : Prostate Adenocarcinoma with Paneth Cell-Like Neuroendocrine Differentiation;

NCIt definition : A prostate adenocarcinoma characterized by the presence of cells with eosinophilic cytoplasmic granules that are positive for neuroendocrine markers by immunohistochemistry.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL950756;

Details

Origin ID

C158664;

UMLS CUI

C5203866;

Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Endothelial Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease excludes normal cell origin
- Endothelial Cell [NCIt concept]
Disease may have findings
- Serum Prostate Specific Antigen Increased [NCIt concept]
Has associated anatomic sites
- Genitourinary System [NCIt concept]
- Male Reproductive System [NCIt concept]
- Prostate Gland [NCIt concept]
- Reproductive System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Expression of Neuroendocrine Markers Present [NCIt concept]
- Invasive Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Paneth Cell-Like Change [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Prostatic Epithelium [NCIt concept]
- Prostatic Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Genitourinary System [NCIt concept]
- Male Reproductive System [NCIt concept]
- Prostate Gland [NCIt concept]
disease_mapped_to_gene
- ERG Gene [NCIt concept]
- TMPRSS2/ERG Fusion Gene [NCIt concept]
disease_may_have_molecular_abnormality
- ERG Gene Rearrangement [NCIt concept]
- TMPRSS2-ERG Fusion Protein Expression [NCIt concept]

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