Autologous Cytotoxic T-lymphocytes Exposed to Dendritic Cells loaded with 6B11 Anti-idiotype Minibody

Preferred Label : Autologous Cytotoxic T-lymphocytes Exposed to Dendritic Cells loaded with 6B11 Anti-idiotype Minibody;

NCIt synonyms : Autologous CTLs Exposed to 6B11mini-ovarian-cytokine-induced-killer Cells; 6B11 Anti-idiotype Minibody-pulsed DCs Induced Autologous CTLs; Autologous CTLs Exposed to 6B11-OCIK; Autologous Cytotoxic T-cells Induced by Autologous Dendritic Cells Loaded with 6B11 Anti-idiotype Minibody; Autologous CTLs Induced with 6B11 Anti-idiotype Minibody-pulsed DCs;

NCIt definition : A preparation of autologous cytotoxic T-lymphocytes (CTLs) that are exposed, ex vivo, to autologous dendritic cells (DCs) loaded with the anti-idiotype minibody 6B11, which mimics the epithelial ovarian tumor-associated antigen (TAA), OC166-9, with potential immunostimulatory and antineoplastic activities. Upon administration, the CTLs exposed to DCs loaded with 6B11 anti-idiotype minibody target and kill autologous ovarian cells expressing the TAA.;

NCI Metathesaurus CUI : CL938078;

Details

Origin ID

C158601;

UMLS CUI

C4764287;

Semantic type(s)
- Cell [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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