" /> tGLI1 Allele - CISMeF





Preferred Label : tGLI1 Allele;

NCIt synonyms : tGLI; Truncated Glioma-Associated Oncogene Homolog 1 Gene; TGLI1; Truncated GLI Family Zinc Finger 1 Allele; Truncated GLI1 Gene;

NCIt definition : Human tGLI1 allele is located in the vicinity of 12q13.3 and is approximately 12 kb in length. This allele, which encodes truncated glioma-associated oncogene homolog 1 protein, is involved in the modulation of transcription by RNA polymerase II. Expression of this allele is associated with glioblastoma multiforme (GBM).;

NCIt note : tGLI1 allele is a splice variant of the GLI1 gene with an in-frame deletion of 123 bases (41 codons), which removes all of exon 3 and part of exon 4.;

NCI Metathesaurus CUI : CL936813;

GenBank Accession Number : NM_001167609;

PubMed : 19706761;

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15/05/2024


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