Thorium Th 227 Anetumab Corixetan

Preferred Label : Thorium Th 227 Anetumab Corixetan;

NCIt synonyms : Thorium Th 227 Monoclonal Antibody BAY2287411; Thorium-227 Labeled Anetumab; Thorium-227 Labeled Antibody-chelator Conjugate BAY2287411; 227Th Anetumab Corixetan;

NCIt related terms : ANETUMAB CORIXETAN THORIUM TH-227;

NCIt definition : A radioimmunoconjugate consisting of anetumab, a human immunoglobulin G1 (IgG1) monoclonal antibody directed against the cell surface glycoprotein mesothelin, conjugated to the chelating agent corixetan, and labeled with the alpha-emitting radioisotope thorium Th 227, with potential antineoplastic activity. Upon administration of thorium Th 227 anetumab corixetan, the anetumab moiety binds to the tumor-associated antigen (TAA) mesothelin, delivering a cytotoxic dose of alpha radiation to cells expressing mesothelin.;

UNII : 22OG9ZC9MN;

CAS number : 2222980-98-3;

Molecule name : BAY2287411; BAY 2287411;

NCI Metathesaurus CUI : CL562713;

Details

Origin ID

C155977;

UMLS CUI

C5442182;

Currated CISMeF NLP mapping
- BAY 2287411 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- BAY 2287411 [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Mesothelin [NCIt concept]

Keyword's position in hierarchy(ies) :

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