" /> Thorium Th 227 Anetumab Corixetan - CISMeF





Preferred Label : Thorium Th 227 Anetumab Corixetan;

NCIt synonyms : Thorium Th 227 Monoclonal Antibody BAY2287411; Thorium-227 Labeled Anetumab; Thorium-227 Labeled Antibody-chelator Conjugate BAY2287411; 227Th Anetumab Corixetan;

NCIt related terms : ANETUMAB CORIXETAN THORIUM TH-227;

NCIt definition : A radioimmunoconjugate consisting of anetumab, a human immunoglobulin G1 (IgG1) monoclonal antibody directed against the cell surface glycoprotein mesothelin, conjugated to the chelating agent corixetan, and labeled with the alpha-emitting radioisotope thorium Th 227, with potential antineoplastic activity. Upon administration of thorium Th 227 anetumab corixetan, the anetumab moiety binds to the tumor-associated antigen (TAA) mesothelin, delivering a cytotoxic dose of alpha radiation to cells expressing mesothelin.;

UNII : 22OG9ZC9MN;

CAS number : 2222980-98-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2222980-98-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : BAY2287411; BAY 2287411;

NCI Metathesaurus CUI : CL562713;

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15/05/2024


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