" /> Autologous Anti-CD19 CAR T-cells IM19 - CISMeF





Preferred Label : Autologous Anti-CD19 CAR T-cells IM19;

NCIt synonyms : Autologous CD19-specific CAR-T Cells IM19; Autologous Anti-CD19 CAR-T Cells IM19;

NCIt definition : A preparation of autologous T-lymphocytes that have been genetically modified and transduced with a lentiviral vector expressing a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD19 and containing, as of yet undisclosed co-stimulatory signaling domains, with potential immunostimulating and antineoplastic activities. Upon administration, autologous anti-CD19 CAR T-cells IM19 target and bind to CD19-expressing tumor cells, thereby inducing selective toxicity in CD19-expressing tumor cells. CD19 antigen is a B-cell specific cell surface antigen expressed in all B-cell lineage malignancies.;

Molecule name : IM19;

NCI Metathesaurus CUI : CL562698;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
15/05/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.