Pyruvate Dehydrogenase Protein X Component, Mitochondrial

Preferred Label : Pyruvate Dehydrogenase Protein X Component, Mitochondrial;

NCIt synonyms : Lipoyl-Containing Pyruvate Dehydrogenase Complex Component X; Dihydrolipoamide Dehydrogenase-Binding Protein of Pyruvate Dehydrogenase Complex; E3BP; Pyruvate Dehydrogenase Complex, Lipoyl-Containing Component X; PDHX; E3-Binding Protein; proX; Pyruvate Dehydrogenase Complex, E3-Binding Protein Subunit;

NCIt definition : Pyruvate dehydrogenase protein X component, mitochondrial (501 aa, 54 kDa) is encoded by the human PDHX gene. This protein plays a role in anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complex.;

NCI Metathesaurus CUI : CL555950;

Details

Origin ID

C155319;

UMLS CUI

C4722665;

Automatic exact mappings (from CISMeF team)
- Pyruvate dehydrogenase complex, component X [OMIM gene]
- pyruvate dehydrogenase complex component X [ORDO Gene]
OMIM relation
- Pyruvate dehydrogenase complex, component X [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- PDHX Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrial Matrix [NCIt concept]
gene_product_has_biochemical_function
- Scaffolding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Proline-Rich Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Energy Metabolism Process [NCIt concept]
- Protein-Protein Interaction [NCIt concept]

Keyword's position in hierarchy(ies) :

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