Preferred Label : Sotorasib;

NCIt definition : An orally available inhibitor of the specific KRAS mutation, p.G12C, with potential antineoplastic activity. Upon oral administration, sotorasib selectively targets, binds to and inhibits the activity of the KRAS p.G12C mutant. This may inhibit growth in KRAS p.G12C-expressing tumor cells. The KRAS p.G12C mutation is seen in some tumor cell types and plays a key role in tumor cell proliferation.;

UNII : 2B2VM6UC8G;

InChIKey : NXQKSXLFSAEQCZ-SFHVURJKSA-N;

CAS number : 2296729-00-3;

Drug name : Lumakras; Lumykras;

Molecule name : AMG 510; AMG-510;

NCI Metathesaurus CUI : CL555284;

Codes from synonyms : 59461;

Détails


Consulter ci-dessous une sélection des principales ressources :

Vous pouvez consulter :


https://www.has-sante.fr/jcms/p_3450915/fr/lumykras-sotorasib-cancer-du-poumon
2023
false
false
false
France
evaluation of the transparency committee
sotorasib
Sotorasib
Lung Carcinoma
lung neoplasms
lung cancer
neoplasm, malignant
sotorasib

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28/07/2025


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