" /> Guretolimod - CISMeF





Preferred Label : Guretolimod;

NCIt synonyms : TLR7 Agonist DSP-0509; Toll-like Receptor 7 Agonist DSP-0509; (((4-((2-Amino-4-(((3s)-1-hydroxyhexan-3-yl)amino)-6-methylpyrimidin-5-yl)methyl)-3- methoxyphenyl)methyl)(2,2,2-trifluoroethyl)amino)acetic Acid;

NCIt definition : A synthetic, small molecule, toll-like receptor (TLR) 7 agonist, with potential immunostimulatory and antineoplastic activities. Upon intravenous administration, guretolimod activates TLR7, resulting in type I interferon secretion and activation of cytotoxic T-lymphocyte (CTL)-mediated anti-tumor immune responses. TLR7 is a member of the TLR family, which plays a fundamental role in pathogen recognition and activation of innate immunity.;

UNII : 2UG29YVL56;

CAS number : 1488364-57-3;

Molecule name : DSP 0509; DSP-0509;

NCI Metathesaurus CUI : CL554427;

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29/07/2025


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