NCIt definition : A wax microsphere capsule formulation of oxycodone, a semi-synthetic, morphine-like
opioid alkaloid, with analgesic activity. Upon administration, oxycodone exerts its
analgesic activity by binding to the mu-receptors in the central nervous system (CNS),
thereby mimicking the effects of endogenous opioids. Due to the unique formulation,
extended-release microsphere capsule-based oxycodone may provide an identical pharmacokinetic
profile regardless of whether the capsule is intact when ingested or if ingested via
enteral feeding tube, leading to a predictable level of analgesia in patients that
must be transitioned from oral to enteral administration.;
Semantic type(s)