Protein Cripto

Preferred Label : Protein Cripto;

NCIt synonyms : TDGF-1; CR-1; CRGF; Cripto Growth Factor; Cripto-1 Growth Factor; Epidermal Growth Factor-Like Cripto Protein CR1; TDGF1; CRIPTO-1; Cripto, EGF-CFC Family Member; CRIPTO;

NCIt related terms : Teratocarcinoma-Derived Growth Factor 1;

NCIt definition : Protein Cripto (188 aa, 21 kDa) is encoded by the human CRIPTO gene. This protein plays a role in growth factor signaling pathways mediated by Nodal homolog.;

NCIt note : Teratocarcinoma-derived growth factor 1 is a member of the EGF-containing Cripto-1/FRL1/Cryptic (EGF-CRC) family of growth factors.;

NCI Metathesaurus CUI : CL554505;

Details

Origin ID

C153277;

UMLS CUI

C4724710;

Automatic exact mappings (from CISMeF team)
- Teratocarcinoma-derived growth factor 1 [OMIM Phenotype]
- teratocarcinoma-derived growth factor 1 [ORDO Gene]
- teratocarcinoma-derived growth factor 1 [HGNC gene]
OMIM relation
- Teratocarcinoma-derived growth factor 1 [OMIM Phenotype]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CRIPTO Gene [NCIt concept]
- Growth Factor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- EGF-Like Domain [NCIt concept]
gene_product_is_element_in_pathway
- Glypican 1 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Morphogenesis [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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