DNMT3 Family - CISMeF

Preferred Label : DNMT3 Family;

NCIt synonyms : DNA (Cytosine-5)-Methyltransferase 3 Family; DNA (Cytosine-5)-Methyltransferase 3; DNMT3;

NCIt definition : A family of proteins involved in methylation of DNA. There are three proteins in this family. DNA (cytosine-5)-methyltransferase (DNMT) 3A and DNMT3B are DNA methyltransferases that catalyze the methylation of hemimethylated and unmethylated CpG at the same rate. DNMT3-like (DNMT3L) has no enzymatic activity; instead this protein interacts with other members of the family and regulates their enzymatic activity.;

NCI Metathesaurus CUI : CL554502;

Details

Origin ID

C153274;

UMLS CUI

C4727141;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_biochemical_function
- DNA Methyltransferase [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Methylation [NCIt concept]
related_to_genetic_biomarker
- DNMT3A Gene [NCIt concept]
- DNMT3B Gene [NCIt concept]
- DNMT3L Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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