" /> Tinodasertib - CISMeF





Preferred Label : Tinodasertib;

NCIt synonyms : MNK1/2 Inhibitor ETC-1907206;

NCIt definition : A selective mitogen-activated protein kinase (MAPK)-interacting protein kinase (MNK) types 1/2 inhibitor with potential antineoplastic activity. Upon administration, tinodasertib may inhibit MNK1/2-dependent phosphorylation of eukaryotic initiation factor 4E (eIF4E) and interfere with its role in mRNA translation. eIF4E is an oncoprotein that must be phosphorylated before it can promote the proliferation and progression of tumor cells. MNKs are a family of serine/threonine kinases that have been implicated in oncogenic transformation and tumor progression.;

UNII : MND3WX2R7I;

CAS number : 1464151-33-4;

Molecule name : ETC 1907206; ETC-206; ETC 206; ETC-1907206; AUM-001;

NCI Metathesaurus CUI : CL554490;

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30/07/2025


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