" /> Vorapaxar Sulfate - CISMeF





Preferred Label : Vorapaxar Sulfate;

NCIt definition : The sulfate salt form of vorapaxar, an orally bioavailable protease-activated receptor-1 (PAR-1) antagonist, with antiplatelet activity. Upon oral administration, vorapaxar binds to PAR-1 expressed on platelets, and inhibits PAR-1-mediated platelet aggregation. Vorapaxar inhibits thrombin-induced and thrombin receptor agonist peptide (TRAP)-induced platelet aggregation, and does not inhibit platelet aggregation induced by adenosine diphosphate (ADP), collagen or a thromboxane mimetic.;

UNII : IN66038E6C;

InChIKey : NQRYCIGCIAWEIC-CKLVGUEFSA-N;

CAS number : 705260-08-8;

Drug name : Zontivity;

Molecule name : SCH 530348;

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25/05/2025


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