NCIt definition : An orally bioavailable protease-activated receptor-1 (PAR-1) antagonist, with antiplatelet
activity. Upon oral administration, vorapaxar binds to PAR-1 expressed on platelets,
and inhibits PAR-1-mediated platelet aggregation. Vorapaxar inhibits thrombin-induced
and thrombin receptor agonist peptide (TRAP)-induced platelet aggregation, and does
not inhibit platelet aggregation induced by adenosine diphosphate (ADP), collagen
or a thromboxane mimetic.;
UNII : ZCE93644N2;
InChIKey : ZBGXUVOIWDMMJE-QHNZEKIYSA-N;
CAS number : 618385-01-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 618385-01-6
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