" /> Vorapaxar - CISMeF





Preferred Label : Vorapaxar;

NCIt definition : An orally bioavailable protease-activated receptor-1 (PAR-1) antagonist, with antiplatelet activity. Upon oral administration, vorapaxar binds to PAR-1 expressed on platelets, and inhibits PAR-1-mediated platelet aggregation. Vorapaxar inhibits thrombin-induced and thrombin receptor agonist peptide (TRAP)-induced platelet aggregation, and does not inhibit platelet aggregation induced by adenosine diphosphate (ADP), collagen or a thromboxane mimetic.;

UNII : ZCE93644N2;

InChIKey : ZBGXUVOIWDMMJE-QHNZEKIYSA-N;

CAS number : 618385-01-6;

Codes from synonyms : 543;

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30/07/2025


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