Vorapaxar - CISMeF

Preferred Label : Vorapaxar;

NCIt definition : An orally bioavailable protease-activated receptor-1 (PAR-1) antagonist, with antiplatelet activity. Upon oral administration, vorapaxar binds to PAR-1 expressed on platelets, and inhibits PAR-1-mediated platelet aggregation. Vorapaxar inhibits thrombin-induced and thrombin receptor agonist peptide (TRAP)-induced platelet aggregation, and does not inhibit platelet aggregation induced by adenosine diphosphate (ADP), collagen or a thromboxane mimetic.;

UNII : ZCE93644N2;

InChIKey : ZBGXUVOIWDMMJE-QHNZEKIYSA-N;

CAS number : 618385-01-6;

Codes from synonyms : 543;

Details

Origin ID

C152912;

UMLS CUI

C2974521;

Automatic exact mappings (from CISMeF team)
- Product containing vorapaxar (medicinal product) [SNOMED CT concept]
- Vorapaxar [ICD-11 Extension code]
- Vorapaxar (substance) [SNOMED CT concept]
- vorapaxar [MeSH concept]
- vorapaxar [MeSH Supplementary Concept]
- vorapaxar [ATC Code]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing vorapaxar (medicinal product) [SNOMED CT concept]
- Vorapaxar (substance) [SNOMED CT concept]
- vorapaxar [ATC Code]
- vorapaxar [MeSH concept]
- vorapaxar [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
has_salt_form
- Vorapaxar Sulfate [NCIt concept]
is_free_acid_or_base_form_of
- Vorapaxar Sulfate [NCIt concept]

Keyword's position in hierarchy(ies) :

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