Vonoprazan - CISMeF

Preferred Label : Vonoprazan;

NCIt definition : A potassium-competitive acid blocker (P-CAB), with acid suppressing activity. Upon oral administration, vonoprazan concentrates in the gastric parietal cells and competitively and reversibly binds to the potassium binding site of the proton pump hydrogen-potassium adenosine triphosphatase (H /K ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H ions into the gastric lumen, the final step in gastric acid production. By inhibiting gastric acid secretion, vonoprazan provides relief and healing in the treatment of various conditions, such as gastroduodenal ulcers and reflux esophagitis.;

UNII : 1R5L3J156G;

InChIKey : BFDBKMOZYNOTPK-UHFFFAOYSA-N;

CAS number : 881681-00-1;

NCI Metathesaurus CUI : CL554243;

Codes from synonyms : 120882;

Details

Origin ID

C152911;

UMLS CUI

C4080009;

Automatic exact mappings (from CISMeF team)
- Vonoprazan [MeSH concept]
- vonoprazan [ATC Code]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- vonoprazan [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
has_salt_form
- Vonoprazan Fumarate [NCIt concept]
is_free_acid_or_base_form_of
- Vonoprazan Fumarate [NCIt concept]

Keyword's position in hierarchy(ies) :

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