" /> Tesevatinib Tosylate - CISMeF





Preferred Label : Tesevatinib Tosylate;

NCIt definition : The tosylate salt form of tesevatinib, an orally bioavailable small-molecule receptor tyrosine kinase (RTK) inhibitor, with potential antineoplastic activity. Upon administration, tesevatinib binds to and inhibits several tyrosine receptor kinases that play major roles in tumor cell proliferation and tumor vascularization, including epidermal growth factor receptor (EGFR; ERBB1), epidermal growth factor receptor 2 (HER2; ERBB2), vascular endothelial growth factor receptor (VEGFR), and ephrin B4 (EphB4). This may result in the inhibition of tumor growth and angiogenesis, and tumor regression.;

UNII : GKB6T21I50;

InChIKey : GQLLAIBEWDUUBQ-QIYAQLFNSA-N;

CAS number : 1000599-06-3;

NCI Metathesaurus CUI : CL553905;

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05/08/2025


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