" /> Telotristat - CISMeF





Preferred Label : Telotristat;

NCIt definition : A tryptophan hydroxylase (TPH) inhibitor, with potential anti-serotonergic activity. Upon administration, telotristat binds to and inhibits the activity of TPH. This may result in a reduction in peripheral serotonin (5-HT) production and improvement of serotonin-mediated gastrointestinal effects such as severe diarrhea. TPH, the rate-limiting enzyme in serotonin biosynthesis, is overexpressed in carcinoid tumor cells.;

UNII : 381V4FCV2Z;

InChIKey : NCLGDOBQAWBXRA-PGRDOPGGSA-N;

CAS number : 1033805-28-5;

NCI Metathesaurus CUI : CL553881;

Codes from synonyms : 483;

Détails


Vous pouvez consulter :


Nous contacter.
25/07/2025


[Accueil] [Haut de page]

© CHU de Rouen. Toute utilisation partielle ou totale de ce document doit mentionner la source.