Remimazolam - CISMeF

Preferred Label : Remimazolam;

NCIt definition : A short-acting benzodiazepine derivative that is structurally related to midazolam, with sedative-hypnotic activity. Upon administration, remimazolam targets and binds to a specific site on the gamma-aminobutyric acid (GABA)-A-chloride ionophore receptor complex located on the neuronal membrane. Binding causes an allosteric modification of the receptor thereby enhancing the affinity of GABA to the receptor leading to an increase in the frequency of chloride-channel opening events, which leads to an increase in chloride ion conductance, neuronal hyperpolarization, inhibition of the action potential, and a decrease in neuronal excitability.;

UNII : 7V4A8U16MB;

InChIKey : CYHWMBVXXDIZNZ-KRWDZBQOSA-N;

CAS number : 308242-62-8;

Molecule name : CNS 7056; CNS-7056;

NCI Metathesaurus CUI : CL553519;

Details

Origin ID

C152187;

UMLS CUI

C3179470;

Currated CISMeF NLP mapping
- Remimazolam [SMS substance]
- Remimazolam (substance) [SNOMED CT concept]
- remimazolam [MeSH Supplementary Concept]
- remimazolam [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing remimazolam (medicinal product) [SNOMED CT concept]
- Remimazolam (substance) [SNOMED CT concept]
- remimazolam [MeSH concept]
- remimazolam [MeSH Supplementary Concept]
- remimazolam [ATC Code]
Validated automatic mappings to BTNT
- remimazolam [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Remimazolam Besylate [NCIt concept]
- Remimazolam Tosylate [NCIt concept]
is_free_acid_or_base_form_of
- Remimazolam Besylate [NCIt concept]
- Remimazolam Tosylate [NCIt concept]

Keyword's position in hierarchy(ies) :

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