NCIt definition : A study that compares two groups of people: those with the disease or condition under
study (cases) and a very similar group of people who do not have the disease or condition
(controls). Researchers study the medical and lifestyle histories of the people in
each group to learn what factors may be associated with the disease or condition.
For example, one group may have been exposed to a particular substance that the other
was not. Also called retrospective study.;
Alternative definition : CDISC: Retrospective study in which individuals with an outcome (cases) are compared
to those who do not have the outcome (controls). (CDISC Glossary); CDISC-GLOSS: Retrospective study in which individuals to an outcome (cases) are compared
with those who do not have the outcome (controls). NOTE: The outcome variable (disease,
event, experience, biomarker) is chosen first, and the exposure is evaluated in cases
vs controls to see whether there is an association between exposure and outcome. [After
AMA Manual of Style] See also outcome, observational study.;
Currated CISMeF NLP mapping