Preferred Label : Indium In 111 Rosopatamab Tetraxetan;
NCIt synonyms : In111-HuJ591; 111In-J591; In111-J591; Indium In 111 Monoclonal Antibody HuJ591;
NCIt definition : A radioimmunoconjugate containing the recombinant humanized monoclonal antibody rosopatamab
directed against the extracellular domain of prostate-specific membrane antigen (PSMA)
and labeled with the gamma-emitting isotope indium 111 (In 111; 111In), with potential
radioimaging application. Upon administration, indium In 111 rosopatamab tetraxetan
targets and binds to PSMA expressed on tumor cells. The use of gamma scintigraphy
allows for the detection and imaging of the radioactive In 111, which can be used
to determine the distribution and tumor localization of PSMA. PSMA is a transmembrane
peptidase that is highly expressed on prostate tumor cells.;
NCI Metathesaurus CUI : CL553192;
Origin ID : C151969;
UMLS CUI : C4726588;
Semantic type(s)
- concept_is_in_subset
- has_target
