Polycystic Kidney Disease Protein 1-Like 2

Preferred Label : Polycystic Kidney Disease Protein 1-Like 2;

NCIt synonyms : PKD1L2; Polycystin-1L2; PC1-Like 2 Protein; Polycystic Kidney Disease 1-Like 2;

NCIt definition : Polycystic kidney disease protein 1-like 2 (2459 aa, 273 kDa) is encoded by the human PKD1L2 gene. This protein may play a role in calcium transport and receptor signaling.;

NCIt note : Caution: PKD1L2 is polymorphic and is expressed both a gene and a pseudogene in the human population. The sequence represented here is one that encodes isoform 1 (Q7Z442-1) of the functional protein. (UniProt and EntrezGene);

Details

Origin ID

C150297;

UMLS CUI

C1565760;

Automatic exact mappings (from CISMeF team)
- Polycystin 1-like 2 [OMIM gene]
OMIM relation
- Polycystin 1-like 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PKD1L2 protein, human [MeSH concept]
- PKD1L2 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- PKD1L2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ion Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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