Preferred Label : Androgen Receptor Antagonist BAY 1161116;
NCIt synonyms : AR Antagonist BAY 1161116;
NCIt definition : An orally bioavailable antagonist of the androgen receptor (AR), with potential antineoplastic
activity. Upon oral administration, AR antagonist BAY 1161116 specifically binds to
AR, inhibits AR activation, and prevents AR-mediated signaling. This inhibits cell
growth in AR-overexpressing tumor cells. AR is overexpressed in prostate cancers and
is involved in proliferation, survival and chemoresistance of tumor cells.;
Molecule name : BAY-1161116; BAY 1161116;
NCI Metathesaurus CUI : CL551148;
Origin ID : C148520;
UMLS CUI : C4725096;
Semantic type(s)
concept_is_in_subset
has_target