Preferred Label : Aurora A Kinase Inhibitor LY3295668;
NCIt related terms : AK-01;
NCIt definition : An orally bioavailable inhibitor of the serine/threonine protein kinase aurora A,
with potential antimitotic and antineoplastic activities. Upon administration, aurora
A kinase inhibitor LY3295668 targets, binds to and inhibits the activity of aurora
A kinase. This may result in disruption of the assembly of the mitotic spindle apparatus,
disruption of chromosome segregation, inhibition of cell division and the induction
of apoptosis in cells overexpressing aurora A kinase. Aurora A kinase, overexpressed
in a wide variety of cancers, plays an essential role in the regulation of spindle
assembly and mitosis.;
UNII : 1WX8O5XV4R;
CAS number : 1919888-06-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1919888-06-4
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Molecule name : AK-01; LY 3295668; AK 01; LY-3295668;
Semantic type(s)