" /> Glofitamab - CISMeF





Preferred Label : Glofitamab;

NCIt synonyms : Anti-CD20 x Anti-CD3 Bispecific Monoclonal Antibody RO7082859;

NCIt definition : A bispecific monoclonal antibody, with potential antineoplastic activity. Glofitamab contains two antigen-recognition sites: one for human CD3, a T cell surface antigen, and one for human CD20, a tumor-associated antigen (TAA) that is exclusively expressed on B-cells during most stages of B-cell development and is often overexpressed in B-cell malignancies. Upon administration, glofitamab binds to both T-cells and CD20-expressing B-lineage tumor cells. The resulting cross-linkage may trigger a potent cytotoxic T-lymphocyte (CTL) response against the CD20-expressing tumor B-cells.;

UNII : 06P3KLK2J8;

CAS number : 2229047-91-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2229047-91-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : RO7082859; RO 7082859;

NCI Metathesaurus CUI : CL551055;

Codes from synonyms : 110791;

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15/05/2024


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