Preferred Label : Gallium Ga 68-P16-093;
NCIt synonyms : [68Ga]P16-093; Gallium-68-P16 093; Ga-68 PSMA-093; Ga-68 PSMA-93; Ga-68 P16-093; [68Ga] HBED-CC-PHENOXY-PSMA;
NCIt definition : A radioconjugate composed of a human prostate specific membrane antigen (PSMA)-targeting
ligand (P16-093) conjugated to the radioisotope gallium Ga 68, via the acyclic radiometal
chelator N,N'-bis [2-hydroxy-5-(carboxyethyl)benzyl] ethylenediamine-N,N'-diacetic
acid (HBED-CC), with potential use as a tracer for PSMA-expressing tumors during positron
emission tomography (PET). Upon intravenous administration of the gallium Ga 68 P16-093,
the P16-093 moiety targets and binds to PSMA-expressing tumor cells. During PET imaging,
PSMA-expressing tumor cells can be detected. PSMA, a tumor-associated antigen (TAA)
and type II transmembrane protein, is expressed on the membrane of prostatic epithelial
cells and overexpressed on prostate tumor cells.;
NCI Metathesaurus CUI : CL551061;
Origin ID : C148484;
UMLS CUI : C4725067;
Semantic type(s)
- concept_is_in_subset
- has_target
