MDS Neoantigen-specific Autologous T-lymphocytes

Preferred Label : MDS Neoantigen-specific Autologous T-lymphocytes;

NCIt synonyms : MDS-specific PACTN Agent; MDS Neoantigen-specific Immunized Autologous T-cells; Personalized MDS Neoantigen-specific Autologous T-lymphocytes; Personalized Adoptive Cellular Therapy Targeting MDS Stem Cell Neoantigens Agent; Autologous T-lymphocytes Targeting Patient-specific MDS Stem Cell Neoantigens; MDS Neoantigen-specific Autologous T-cells;

NCIt definition : A preparation of autologous T-lymphocytes that are exposed, ex vivo, to multiple, patient-specific myelodysplastic syndrome (MDS) stem cell neoantigens, with potential immunostimulating and antineoplastic activities. Upon infusion of the MDS neoantigen-specific autologous T-lymphocytes, the immunized T-cells specifically target and lyse cells expressing the MDS neoantigens.;

NCI Metathesaurus CUI : CL551016;

Details

Origin ID

C148393;

UMLS CUI

C4725001;

Semantic type(s)
- Cell [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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