Insulinoma-Associated Protein 2

Preferred Label : Insulinoma-Associated Protein 2;

NCIt synonyms : INSM2; Insulinoma-Associated Protein IA-6; Zinc Finger Protein IA-6;

NCIt related terms : IA-2;

NCIt definition : Insulinoma-associated protein 2 (566 aa, 59 kDa) is encoded by the human INSM2 gene. This protein plays a role in cell growth regulation and tumor suppression.;

Alternative definition : CDISC: An antigen encoded by the INSM2 gene and regulates insulin secretion. It can be considered as an autoantigen and is commonly associated with the autoimmune disease type 1 diabetes.;

NCI Metathesaurus CUI : CL550886;

Details

Origin ID

C148305;

UMLS CUI

C4724366;

Automatic exact mappings (from CISMeF team)
- Insulinoma-associated 2 [OMIM gene]
- Protein-tyrosine phosphatase, receptor-type, n [OMIM gene]
- Receptor-Like protein tyrosine phosphatases, class 8 [MeSH Descriptor]
OMIM relation
- Insulinoma-associated 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
gene_encodes_gene_product
- INSM2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2H2 Zinc Finger [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Growth Regulation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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