Neo-multiple TAA-loaded Dendritic Cell Vaccine

Preferred Label : Neo-multiple TAA-loaded Dendritic Cell Vaccine;

NCIt synonyms : neo-MASCT; Neo-multiple TAA-loaded DC Vaccine; Neoantigen-loaded Dendritic Cell Vaccine;

NCIt definition : An autologous dendritic cell (DC) vaccine composed of DCs loaded with multiple distinct neoantigens, with potential immunomodulating and antineoplastic activities. Upon administration, the neo-multiple tumor-associated antigens (TAA)-loaded DC vaccine may stimulate a cytotoxic T-lymphocyte (CTL)-mediated immune response against the tumor cells expressing these neoantigens.;

NCI Metathesaurus CUI : CL550879;

Details

Origin ID

C148188;

UMLS CUI

C4724885;

Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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