Fibroblast Growth Factor 12

Preferred Label : Fibroblast Growth Factor 12;

NCIt synonyms : Fibroblast Growth Factor Homologous Factor 1; Myocyte-Activating Factor; FGF12; FHF-1; FGF-12; Fibroblast Growth Factor-12;

NCIt definition : Fibroblast growth factor 12 (243 aa, 27 kDa) is encoded by the human FGF12 gene. This protein plays a role in both nervous system development and the promotion of voltage-gated sodium channel activity in neurons.;

NCIt note : Fibroblast growth factor 12 (FGF-12) lacks the signal sequence present at the N-terminus of most of the FGF family members. Instead, FGF-12 contains clusters of basic residues that act as a nuclear localization signal. (EntrezGene);

Details

Origin ID

C147997;

UMLS CUI

C1436266;

OMIM relation
- Fibroblast growth factor 12 [OMIM gene]
See also inter- (CISMeF)
- Fibroblast growth factor 12 [OMIM gene]
- fibroblast growth factor 12 [ORDO Gene]
- fibroblast growth factor 12 [HGNC gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- FGF12 protein, human [MeSH Supplementary Concept]
- FGF12 protein, human [MeSH concept]
gene_encodes_gene_product
- FGF12 Gene [NCIt concept]
- Fibroblast Growth Factor Gene Family [NCIt concept]
- Growth Factor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Heparin Binding Growth Factor [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Heparin Binding [NCIt concept]
- Nervous System Development [NCIt concept]
- Neuronal Transmission [NCIt concept]
- Receptor Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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