Inner Nuclear Membrane Protein Man1

Preferred Label : Inner Nuclear Membrane Protein Man1;

NCIt synonyms : Integral Inner Nuclear Membrane Protein; LEM Domain-Containing Protein 3; LEMD3; MAN Antigen 1;

NCIt definition : Inner nuclear membrane protein Man1 (911 aa, 100 kDa) is encoded by the human LEMD3 gene. This protein is involved in the negative regulation of transforming growth factor beta (TGF-B) receptor signaling.;

Details

Origin ID

C147954;

UMLS CUI

C1438822;

Automatic exact mappings (from CISMeF team)
- Ankyrin repeat- and lem domain-containing protein 1 [OMIM gene]
- LEM domain containing 3 [ORDO Gene]
- LEM domain containing 3 [HGNC gene]
- Lem domain-containing protein 3 [OMIM gene]
OMIM relation
- Lem domain-containing protein 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- LEMD3 protein, human [MeSH Supplementary Concept]
- LEMD3 protein, human [MeSH concept]
gene_encodes_gene_product
- LEMD3 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nuclear Inner Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Signal Transduction Inhibition [NCIt concept]

Keyword's position in hierarchy(ies) :

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