Cocaine- and Amphetamine-Regulated Transcript Protein

Preferred Label : Cocaine- and Amphetamine-Regulated Transcript Protein;

NCIt synonyms : CART; CARTPT; CART Prepropeptide;

NCIt definition : Cocaine- and amphetamine-regulated transcript protein (116 aa, 13 kDa) is encoded by the human CARTPT gene. This protein plays a role in the inhibition of appetite.;

NCIt note : Cocaine- and amphetamine-regulated transcript protein is cleaved by prohormone convertases to produce 2 biologically active peptides CART (1-39), which is composed of amino acids 28-66, and CART (42-89), which is composed of amino acids 69-116. (UniProt);

Details

Origin ID

C147930;

UMLS CUI

C1738809;

Automatic exact mappings (from CISMeF team)
- CART [OBI concept]
- CART prepropeptide [HGNC gene]
- Cart prepropeptide [OMIM gene]
- Cart, device (physical object) [SNOMED CT concept]
- Carts [ICD-11 Extension code]
- cart [SNOMED Notion]
- cocaine- and amphetamine-regulated transcript protein [MeSH Supplementary Concept]
- cocaine- and amphetamine-regulated transcript protein [MeSH concept]
OMIM relation
- Cart prepropeptide [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CART protein, human [MeSH concept]
gene_encodes_gene_product
- CARTPT Gene [NCIt concept]
gene_product_expressed_in_tissue
- Hypothalamus [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_plays_role_in_biological_process
- Appetite [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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