NCIt related terms : 18; HPV 18; HUMAN PAPILLOMAVIRUS TYPE 18;
NCIt definition : A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded
DNA organized into coding and non-coding regions, which can induce skin and mucosal
epithelial lesions. Human papillomavirus-18 (HPV18) has been directly linked to cervical
cancer and plays a role in the pathogenesis of the disease. The virus integrates its
DNA at specific chromosomal locations, such as 8q24 and 12q15. The use of molecular
markers for HPV18 infection may allow the identification of patients with early stage
cervical cancer and those at high risk for disease recurrence.;
Alternative definition : CDISC: Any viral organism that can be assigned to the Human papillomavirus virus type
18 serotype.;