" /> Recombinant CD40-Ligand - CISMeF





Preferred Label : Recombinant CD40-Ligand;

NCIt synonyms : TRAP Ligand; gp39; T-BAM; CD40L; T-Cell Antigen gp39; TNF-Related Activation Protein; rhu CD40L; CD154 antigen; Therapeutic CD40-Ligand;

NCIt definition : A recombinant therapeutic agent which is chemically identical to or similar to CD40-ligand. CD40-ligand, also known as CD40L/TRAP and CD154, is a type II membrane protein which binds to CD40, a cell surface receptor that belongs to the tumor necrosis factor receptor family; CD40 is expressed on B lymphocytes, monocytes, dendritic cells (DC), hematopoietic progenitors, endothelial cells and epithelial cells. Recombinant CD40-ligand may be used to activate DC ex vivo via CD40 binding; CD40-ligand-activated DC may provide or augment a protective antitumor immunity when administered in dendritic cell cancer vaccines. (NCI04);

CAS number : 147205-72-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 147205-72-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

NSC code : 696600;

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10/05/2024


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