Preferred Label : Histone H3 Trimethyl Lys36;
NCIt synonyms : Trimethylated Histone H3 at Lysine 36; Histone H3 Trimethyl Lysine 36; Histone H3 Trimethyl Lysine 37; Histone H3 Trimethyl Lys37;
NCIt related terms : H3K36me3;
NCIt definition : A post-translationally modified form of histone H3 where the lysine residue at position
36 is trimethylated. This modification may be involved in defining exon boundaries;
it also may be a marker for genes targeted for transcriptional repression.;
NCIt note : Even though the literature refers to lysine 36 methylation or amino acid variation/mutation,
RefSeq indicates that the lysine is located at amino acid position 37 in histone H3.
(see also https://link.springer.com/article/10.1007/s00401-018-1867-2);
NCI Metathesaurus CUI : CL540739;
Origin ID : C142872;
UMLS CUI : C4684882;
Semantic type(s)
- concept_is_in_subset
- related_to_genetic_biomarker
