" /> Clodronate Disodium - CISMeF





Preferred Label : Clodronate Disodium;

NCIt synonyms : Clodronic Acid Disodium Salt; Dichloromethylene Diphosphonate; Clodronate;

NCIt related terms : Bonefos;

NCIt definition : The disodium salt of a nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. Clodronate binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. This agent may control malignancy-associated hypercalcemia, inhibit osteolytic bone metastasis and decrease pain.;

Alternative definition : NCI-GLOSS: A drug used as treatment for hypercalcemia (abnormally high levels of calcium in the blood) and for cancer that has spread to the bone (bone metastases). It may decrease pain, the risk of fractures, and the development of new bone metastases.;

UNII : N030400H8J;

InChIKey : XWHPUCFOTRBMGS-UHFFFAOYSA-L;

CAS number : 88416-50-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 88416-50-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Ossiten; Clasteon; Loron; Mebonat; Bonefos; Difosfonal;

Molecule name : CL2MDP;

Chemical formula : CH2Cl2O6P2.2Na.4H2O;

NSC code : 713466;

ChEBI ID : CHEBI:59587;

Codes from synonyms : NSC0713466; CDR0000045405;

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15/05/2024


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